“Compound
active ingredients: guaifenesin, liquid extract for Novo-Passit;
1 ml of solution contains: extract for Novo-Passit liquid (Hyperici herba (St. John’s wort herb), Passiflorae herba (passionflower herb), Valerianae radix (valerian root), Crataegi folium cum flore (leaves and flowers of hawthorn), Lupuli flos (, Melissae herba (lemon balm herb), Sambusi flos (elderberry flowers)) (1:13, extractant water) 0.0775 g, guaifenesin 0.04 g;
other ingredients: sodium cyclamate, xanthan gum, invert sugar, sodium saccharin, sodium benzoate (E 211), ethanol 96%, orange flavor, sodium citrate, maltodextrin, propylene glycol, purified water.
Release form
Oral solution.
Indications
A mild form of neurasthenia, especially accompanied by anxiety, fear, sadness, irritability, increased fatigue or decreased concentration, mild forms of insomnia, asthenia or neurotic memory impairment. maintenance therapy for migraines, headaches caused by nervous tension; vascular psychosomatic disorders with neurocirculatory asthenia, neurogenic tetany, pain in the face; climacteric syndrome. functional diseases of the gastrointestinal tract, dyspeptic syndrome without organic lesions, irritable bowel syndrome and additional therapy for organic diseases of the gastrointestinal tract of neurotic origin. psychosomatic dermatoses accompanied by itching (atopic eczema, urticaria).
Contraindications
Hypersensitivity to the active substances or auxiliary components of the drug; myasthenia gravis; simultaneous use of cyclosporine or tacrolimus; depression and other conditions accompanied by depression of the central nervous system; bradycardia.
Application
For the drug in the form of a solution, the drug is usually prescribed 5 ml (1 teaspoon) 3 times a day. if necessary, the dose is increased to 10 ml 3 times a day or reduced to 2.5 ml in the morning and afternoon and 5 ml in the evening. the dose can be changed according to the patient’s condition. the intervals between taking the drug should be 4-6 hours. The maximum daily dose is 30 ml.
The drug can be mixed with drinks (juice, except grapefruit, tea).
special instructions
The drug should be used with caution in severe liver and kidney diseases, intoxication with substances that suppress the central nervous system.
When using the drug, patients, especially those with fair skin, should avoid prolonged exposure to UV radiation (sunbathing, solarium, diathermy).
Patients receiving treatment with indinavir or other antiretroviral drugs should avoid the use of St. John’s wort as it may lead to the development of antiretroviral drug resistance and reduced effectiveness of treatment.
St. John’s wort and antidepressants such as selective serotonin reuptake inhibitors or triptans should not be used simultaneously.
Use with caution in patients with severe organic diseases of the digestive tract.
In elderly patients, treatment should begin with a minimum dose.
While using the drug, you should refrain from alcoholic beverages.
There may be a specific sensitivity to the smell of valerian.
Guaifenesin should be discontinued 48 hours before urine collection for analysis of vanillylmandelic acid and 5-hydroxyindoleacetic acid in urine using nitrosonaphthol as a reagent.
The drug in solution form contains 12.19% vol. ethanol, one dose (5 ml) contains 0.481 g of ethanol, which should be taken into account when used during pregnancy and lactation, in children and patients at risk (with liver disease, epilepsy, alcoholism).
One dose (5 ml) of the solution contains 1.99 g of a mixture of fructose and glucose. This should be taken into account when treating patients with diabetes. The drug should not be used in patients with hereditary galactose intolerance, lactase deficiency or glucose-galactose malabsorption.
During pregnancy and breastfeeding
Given the insufficient data on the safety of the drug during pregnancy and breastfeeding, its use during this period is contraindicated.
Children
The drug is prescribed to children over 12 years of age.
For drivers
Due to the fact that Novo-Passit contains ethanol and guaifenesin, when using the drug, a decrease in the speed of psychomotor reactions is possible, which manifests itself individually in each patient (see Side effects). Therefore, you should refrain from potentially hazardous activities that require increased attention, such as driving vehicles or operating other machinery.”
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