“Composition
Dry extract of St. John’s wort, (3-7:1), extractant: methanol 80% (vol/vol) 600 mg, Ascorbic acid, Microcrystalline cellulose, Croscarmellose, sodium salt, Iron (III) hydroxide oxide, Hypromellose, Magnesium stearate (Ph. Eur.) [vegetable], Saccharin, sodium salt, Precipitated silicon dioxide, Stearic acid, Titanium dioxide, Vanillin, Total sodium ions 23 mg
Scope
The drug is a herbal remedy for depressive moods.
The drug is used for:
mild depressive episodes (disorders).
Dosage
Unless otherwise prescribed by your doctor, the usual dose is:
Adults (18 years and over):
Take 1 film-coated tablet once daily in the morning (equivalent to 600 mg of St. John’s wort extract per day).
Duration of use:
Experience has shown that a period of 4-6 weeks is required for significant improvement of symptoms; However, if symptoms persist for more than 4 weeks or worsen despite taking the prescribed dosage, you should consult your doctor again.
The medicine should not be taken
in severe temporary depressive disorders, as there is insufficient data on this subject.
during pregnancy.
in severe temporary depressive disorders;
The medicinal product must not be used together with the active substances of the following classes of drugs, which are broken down and excreted by certain liver enzymes (cytochrome P450-3A4, CYP2C9, CYP2C19) or by a specific drug transport system (P-glycoprotein):
Medicines for the treatment of HIV (“”AIDS””), such as indinavir and nevirapine;
Protease inhibitors for the treatment of hepatitis C infections, such as telaprevir;
Immunosuppressants, such as cyclosporine and tacrolimus;
Medicines that inhibit cell growth in the treatment of cancer, such as irinotecan; Imatinib and related substances (protein kinase inhibitors); Vinca alkaloids; Taxanes; Etoposide; Cyclophosphamide;
Coumarin-type anticoagulants, such as warfarin.
In addition, the product must not be taken together with other medicines for the treatment of depression (antidepressants).
Should not be used in case of hypersensitivity to the active ingredient or any of the other ingredients, or if the skin is known to be hypersensitive to light.”
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