“Compound
100 ml of syrup contains:
active substance:
carbocisteine lysine salt monohydrate 9 g,
Excipients:
sucrose – 40 g;
natural cherry essence – 0.25 g;
methyl p-hydroxybenzoate – 0.15 g;
caramel – 0.03 g;
purified water – up to 100 ml
The mucolytic and expectorant effect of carbocysteine lysine salt is due to the activation of sialic transferase (an enzyme of goblet cells of the bronchial mucosa). Normalizes the quantitative ratio of acidic and neutral mucins in bronchial secretions: reduces the amount of neutral glycopeptides, increases the amount of hydroxysialoglycopeptides. Reduces the viscosity of bronchial secretions and discharge from the paranasal sinuses, facilitates the discharge of sputum and mucus, and reduces cough. Promotes the regeneration of the mucous membrane, normalizes its structure, reduces the number of goblet cells, especially in the terminal bronchi and, as a result, reduces mucus production. Restores the secretion of immunologically active IgA (specific protection), improves mucociliary clearance and transport of antibiotics.
In addition, carbocisteine lysine salt stimulates the secretion of chlorine ions in the epithelium of the respiratory tract. This phenomenon is associated with the transport of water and, thus, with the liquefaction of mucous secretions. Carbocysteine lysine salt increases the concentration of lactoferrin, lysozyme and α1-antitrypsin, which indicates the functional restoration of the mucous cells of the bronchial glands and their protein synthesis mechanism.
Carbocysteine lysine salt is a neutral compound (pH 6.8), is highly soluble in water and therefore does not irritate the gastric mucosa, which allows the daily dose to be prescribed at one time.
Indications
Acute and chronic bronchopulmonary diseases, accompanied by the formation of viscous and difficult to separate sputum (tracheitis, bronchitis, tracheobronchitis, bronchial asthma, bronchiectasis) and mucus (inflammatory diseases of the middle ear and paranasal sinuses – rhinitis, adenoiditis, otitis media, sinusitis).
Preparing the patient for bronchoscopy or bronchography.
Contraindications
Hypersensitivity to any component of the drug;
Peptic ulcer of the stomach and duodenum (in the acute phase);
Pregnancy;
Children under 2 years of age;
Sucrase/isomaltase deficiency;
Fructose intolerance;
Glucose-galactose malabsorption (since the drug contains sucrose).”
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